ChEMBL ligand: CHEMBL1394231
Erythrocyte urea transporter/Urea transporter 1 in Human [ChEMBL: CHEMBL2390814] [GtoPdb: 982] [UniProtKB: Q13336] Erythrocyte urea transporter/Urea transporter 1 in Mouse [ChEMBL: CHEMBL2163171] [GtoPdb: 982] [UniProtKB: Q8VHL0] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Erythrocyte urea transporter/Urea transporter 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2390814] [GtoPdb: 982] [UniProtKB: Q13336]
ChEMBL	Inhibition of UT-B in human erythrocytes assessed as increase of hypotonic lysis	B	7.96	pIC50	11	nM	IC50	Bioorg. Med. Chem. Lett. (2013) 23: 3338-3341 [PMID:23597791]
GtoPdb	-	-	7.96	pIC50	~11	nM	IC50	Bioorg Med Chem Lett (2013) 23: 3338-41 [PMID:23597791]
Erythrocyte urea transporter/Urea transporter 1 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2163171] [GtoPdb: 982] [UniProtKB: Q8VHL0]
GtoPdb	-	-	7.6	pIC50	25	nM	IC50	Bioorg Med Chem Lett (2013) 23: 3338-41 [PMID:23597791]
ChEMBL	Reversible inhibition of mouse UT-B-mediated urea transport	B	7.6	pIC50	25.1	nM	IC50	J. Med. Chem. (2012) 55: 5942-5950 [PMID:22694147]
ChEMBL	Inhibition of UT-B in wild type CD1 mouse erythrocyte assessed as hemolysis after 10 mins	B	7.96	pIC50	11	nM	IC50	J. Med. Chem. (2012) 55: 5942-5950 [PMID:22694147]
ChEMBL	Inhibition of UT-B in mouse acetamide-loaded erythrocyte assessed as increase of hypotonic lysis	B	7.96	pIC50	11	nM	IC50	Bioorg. Med. Chem. Lett. (2013) 23: 3338-3341 [PMID:23597791]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]