ChEMBL ligand: CHEMBL1644 (Anhydrous cefadroxil, Baxan, BL-S578, Cefadrops, Cefadroxil, Cefadroxil anhydrous, Cefadroxil (as monohydrate), Cefadroxil/cefadroxil hemihydrate, Cefadroxil hydrate, Cefadroxil monohydrate, Cefatabs, Duracef, Duricef, MJF 11567-3, MJF-11567-3, NSC-756664, Ultracef)
Peptide transporter 2/Oligopeptide transporter, kidney isoform in Rat [ChEMBL: CHEMBL3325] [GtoPdb: 985] [UniProtKB: Q63424] There should be some charts here, you may need to enable JavaScript!
Peptide transporter 2/Solute carrier family 15 member 2 in Human [ChEMBL: CHEMBL1743125] [GtoPdb: 985] [UniProtKB: Q16348] There should be some charts here, you may need to enable JavaScript!
Organic anion transporter 1/Solute carrier family 22 member 6 in Human [ChEMBL: CHEMBL1641347] [GtoPdb: 1025] [UniProtKB: Q4U2R8] There should be some charts here, you may need to enable JavaScript!
Organic anion transporter 3/Solute carrier family 22 member 8 in Human [ChEMBL: CHEMBL1641348] [GtoPdb: 1027] [UniProtKB: Q8TCC7] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Peptide transporter 2/Oligopeptide transporter, kidney isoform in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3325] [GtoPdb: 985] [UniProtKB: Q63424]
ChEMBL	TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cells	F	5.52	pKi	3000	nM	Ki	Eur J Pharm Biopharm (2005) 59: 17-24 [PMID:15567297]
ChEMBL	TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells	F	5.52	pKi	3000	nM	Ki	Am J Physiol (1997) 273: F706-F711 [PMID:9374833]
Peptide transporter 2/Solute carrier family 15 member 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1743125] [GtoPdb: 985] [UniProtKB: Q16348]
ChEMBL	TP_TRANSPORTER: inhibition of Gly-Sar uptake in SKPT cells	F	5.55	pKi	2800	nM	Ki	J Biol Chem (1995) 270: 25672-25677 [PMID:7592745]
ChEMBL	TP_TRANSPORTER: inhibition of Chephalexin uptake in SKPT cells	F	5.6	pKi	2500	nM	Ki	J Biol Chem (1995) 270: 25672-25677 [PMID:7592745]
ChEMBL	TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 50 uM) in PEPT2-expressing HeLa cells	F	4.18	pIC50	66000	nM	IC50	J Biol Chem (1995) 270: 25672-25677 [PMID:7592745]
Organic anion transporter 1/Solute carrier family 22 member 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1641347] [GtoPdb: 1025] [UniProtKB: Q4U2R8]
ChEMBL	TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells	F	5.21	pKi	6140	nM	Ki	Eur J Pharmacol (2002) 438: 137-142 [PMID:11909604]
Organic anion transporter 3/Solute carrier family 22 member 8 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1641348] [GtoPdb: 1027] [UniProtKB: Q8TCC7]
ChEMBL	TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cells	F	5.06	pKi	8620	nM	Ki	Eur J Pharmacol (2002) 438: 137-142 [PMID:11909604]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]