FGF-21   Click here for help

GtoPdb Ligand ID: 11721

Synonyms: fibroblast growth factor 21
Comment: FGF21 is a mitogen that is involved in the migration and differentiation of cells that are of mesodermal or neuroectodermal origin, and in metabolic regulation [2]. Klotho beta (KLB) appears to be required for FGF21's metabolic activity [3]. The peptide sequence provided here includes the signal peptide (MDSDETGFEHSGLWVSVLAGLLLGACQA).
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Fibroblast growth factor (FGF) family ligands
Synonyms Click here for help
fibroblast growth factor 21
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
FGF21 fibroblast growth factor 21 Human fibroblast growth factor 21 precursor -
Database Links Click here for help
Ensembl Gene ENSG00000134962 (Hs)
Entrez Gene 26291 (Hs)
GtoPdb PubChem SID 458923756
Human Protein Atlas ENSG00000134962 (Hs)
RefSeq Nucleotide NM_019113 (Hs)
RefSeq Protein NP_061986 (Hs)
UniProtKB Q9NSA1 (Hs)