chlorpropamide   

GtoPdb Ligand ID: 6801

Synonyms: Diabenese® | Glucamide®
chlorpropamide is an approved drug (FDA (1958))
Compound class: Synthetic organic
Comment: A sulfonylurea family drug inhibiting sulfonylurea receptor 1 (ABCC8)/Kir6.2 (KCNJ11)
2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 83.65
Molecular weight 276.03
XLogP 1.8
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
Isomeric SMILES CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
InChI InChI=1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
InChI Key RKWGIWYCVPQPMF-UHFFFAOYSA-N
Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1958))
IUPAC Name
1-(4-chlorobenzenesulfonyl)-3-propylurea
International Nonproprietary Names
INN number INN
790 chlorpropamide
Synonyms
Diabenese® | Glucamide®
Database Links
CAS Registry No. 94-20-2
ChEMBL Ligand CHEMBL498
DrugBank Ligand DB00672
DrugCentral Ligand 622
GtoPdb PubChem SID 178103407
PubChem CID 2727
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Wikipedia Chlorpropamide