chlorpropamide   Click here for help

GtoPdb Ligand ID: 6801

Synonyms: Diabenese® | Glucamide®
Approved drug
chlorpropamide is an approved drug (FDA (1958))
Compound class: Synthetic organic
Comment: A sulfonylurea family drug inhibiting sulfonylurea receptor 1 (ABCC8)/Kir6.2 (KCNJ11)
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 83.65
Molecular weight 276.03
XLogP 1.8
No. Lipinski's rules broken 0
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Canonical SMILES CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
Isomeric SMILES CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
InChI InChI=1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1958))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
790 chlorpropamide
Synonyms Click here for help
Diabenese® | Glucamide®
Database Links Click here for help
CAS Registry No. 94-20-2
DrugBank Ligand DB00672
DrugCentral Ligand 622
GtoPdb PubChem SID 178103407
PubChem CID 2727
Search Google for chemical match using the InChIKey RKWGIWYCVPQPMF-UHFFFAOYSA-N
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Search PubMed clinical trials chlorpropamide
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UniChem Compound Search for chemical match using the InChIKey RKWGIWYCVPQPMF-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey RKWGIWYCVPQPMF-UHFFFAOYSA-N
Wikipedia Chlorpropamide