carbidopa   

GtoPdb Ligand ID: 5159

Synonyms: Duodopa® | Lodosyn®
carbidopa is an approved drug (FDA (1977))
Compound class: Synthetic organic
Comment: Carbidopa was originally approved by the FDA in combination with levodopa in 1975. Carbidopa is a noncompetitive decarboxylase inhibitor.
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2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 5
Rotatable bonds 4
Topological polar surface area 115.81
Molecular weight 226.1
XLogP 0.02
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES NNC(C(=O)O)(Cc1ccc(c(c1)O)O)C
Isomeric SMILES NN[C@](C(=O)O)(Cc1ccc(c(c1)O)O)C
InChI InChI=1S/C10H14N2O4/c1-10(12-11,9(15)16)5-6-2-3-7(13)8(14)4-6/h2-4,12-14H,5,11H2,1H3,(H,15,16)/t10-/m0/s1
InChI Key TZFNLOMSOLWIDK-JTQLQIEISA-N
Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1977))
IUPAC Name
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
International Nonproprietary Names
INN number INN
3258 carbidopa
Synonyms
Duodopa® | Lodosyn®
Database Links
CAS Registry No. 28860-95-9
ChEBI CHEBI:39585
ChEMBL Ligand CHEMBL1201236
DrugBank Ligand DB00190
DrugCentral Ligand 496
GtoPdb PubChem SID 178101851
PubChem CID 34359
RCSB PDB Ligand 142
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Wikipedia Carbidopa

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Tocris
(S)-(-)-Carbidopa
Cat. No. 0455