WAY-100635 [Ligand Id: 80] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL31354
  • 5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908]
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  • D4 receptor in Human [GtoPdb: 217] [UniProtKB: P21917]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908]
GtoPdb - - 9.2 pKi 0.63 nM Ki Eur. J. Pharmacol. (1998) 355: 245-56 [PMID:9760039];
Naunyn Schmiedebergs Arch. Pharmacol. (1998) 357: 205-17 [PMID:9550290]
D4 receptor in Human [GtoPdb: 217] [UniProtKB: P21917]
GtoPdb - - 7.8 pKi 16 nM Ki J. Med. Chem. (2011) 54: 3480-91 [PMID:21520940]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]