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ChEMBL ligand: CHEMBL8085 (Lysine) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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glutathione-disulfide reductase/Glutathione reductase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2755] [GtoPdb: 2613] [UniProtKB: P00390] | ||||||||
ChEMBL | Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis | B | 4.26 | pKi | 54600 | nM | Ki | Bioorg Med Chem Lett (2011) 21: 5398-5402 [PMID:21795044] |
ChEMBL | Inhibition of human erythrocyte Glutathione reductase | B | 4.21 | pIC50 | 61200 | nM | IC50 | Bioorg Med Chem Lett (2011) 21: 5398-5402 [PMID:21795044] |
GPRC6 receptor in Human [GtoPdb: 55] [UniProtKB: Q5T6X5] | ||||||||
GtoPdb | - | - | 3.8 | pEC50 | - | - | - | Mol Pharmacol (2005) 67: 589-97 [PMID:15576628] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]