[125I]CGP 71872 [Ligand Id: 1077] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1628548 (CGP-71872)
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  • GABAB receptor in Rat [GtoPdb: 242]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GABAB2/GABAB1/GABA-B receptor in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL2111463] [GtoPdb: 241, 240] [UniProtKB: O75899, Q9UBS5]
ChEMBL Binding affinity to GABA-B receptor (unknown origin) B 9 pKd 1 nM Kd J. Med. Chem. (2015) 58: 6336-6347 [PMID:25856547]
GABAB2/GABAB1 in Rat [GtoPdb: 241, 240] [UniProtKB: O88871, Q9Z0U4]
GtoPdb - - 9 pKd - - - Nature (1997) 386: 239-46 [PMID:9069281]
GABAB receptor in Rat [GtoPdb: 242]
GtoPdb - - 9 pKd 1 nM Kd Nature (1997) 386: 239-46 [PMID:9069281]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]