[125I]CGP 71872 [Ligand Id: 1077] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1628548 (CGP-71872)
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  • GABAB receptor in Rat [GtoPdb: 242]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GABAB2/GABAB1/GABA-B receptor in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL2111463] [GtoPdb: 241, 240] [UniProtKB: O75899, Q9UBS5]
ChEMBL Binding affinity to GABA-B receptor (unknown origin) B 9 pKd 1 nM Kd J Med Chem (2015) 58: 6336-6347 [PMID:25856547]
GABAB2/GABAB1 in Rat [GtoPdb: 241, 240] [UniProtKB: O88871, Q9Z0U4]
GtoPdb - - 9 pKd - - - Nature (1997) 386: 239-46 [PMID:9069281]
GABAB receptor in Rat [GtoPdb: 242]
GtoPdb - - 9 pKd 1 nM Kd Nature (1997) 386: 239-46 [PMID:9069281]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]