ChEMBL ligand: CHEMBL3260772
EP4 receptor/Prostanoid EP4 receptor in Human [ChEMBL: CHEMBL1836] [GtoPdb: 343] [UniProtKB: P35408] EP4 receptor in Mouse [GtoPdb: 343] [UniProtKB: P32240] There should be some charts here, you may need to enable JavaScript!
EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
EP4 receptor/Prostanoid EP4 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1836] [GtoPdb: 343] [UniProtKB: P35408]
ChEMBL	Displacement of [3H]PGE2 from human prostanoid EP4 receptor expressed in cell membranes by scintillation counting	B	8.15	pKi	7	nM	Ki	Bioorg Med Chem Lett (2014) 24: 2212-2221 [PMID:24703233]
EP4 receptor in Mouse [GtoPdb: 343] [UniProtKB: P32240]
GtoPdb	-	-	8.57	pKi	2.7	nM	Ki	Cancer Res (2002) 62: 28-32 [PMID:11782353]
EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557]
GtoPdb	-	-	7.68	pKi	21	nM	Ki	Cancer Res (2002) 62: 28-32 [PMID:11782353]
GtoPdb	-	-	6.8	pIC50	160	nM	IC50	Cancer Res (2002) 62: 28-32 [PMID:11782353]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]