Synonyms: pyrrolidinylmethyltetracycline | Reverin® | SQ 15,659 | Syntetrin® | Velacycline®
rolitetracycline is an approved drug (FDA (1959))
Compound class:
Synthetic organic
Comment: Rolitetracycline is a parenterally delivered prodrug of tetracycline, an antibacterial that has activity against Gram-negative and Gram-positive bacteria.
Note that the structure shown here matches the CAS-assigned structure and is the same as the ChEBI and ChEMBL entries linked to below. There is no exact match in PubChem for the structure shown here. |
|
Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1959)) |
Withdrawn drug? | Yes |
Is prodrug? | Yes |
Active form | tetracycline |
IUPAC Name |
(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-[(pyrrolidin-1-yl)methyl]-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide |
International Nonproprietary Names | |
INN number | INN |
1041 | rolitetracycline |
Synonyms |
pyrrolidinylmethyltetracycline | Reverin® | SQ 15,659 | Syntetrin® | Velacycline® |
Database Links | |
Specialist databases | |
Antibiotic DB | Rolitetracycline |
Other databases | |
BindingDB Ligand | 50477463 |
CAS Registry No. | 751-97-3 (source: Scifinder) |
ChEBI | CHEBI:63334 |
ChEMBL Ligand | CHEMBL1237046 |
DrugBank Ligand | DB01301 |
DrugCentral Ligand | 2399 |
GtoPdb PubChem SID | 483123308 |
PubChem CID | 54682938 |
Search Google for chemical match using the InChIKey | HMEYVGGHISAPJR-IAHYZSEUSA-N |
Search Google for chemicals with the same backbone | HMEYVGGHISAPJR |
Search PubMed clinical trials | rolitetracycline |
Search PubMed titles | rolitetracycline |
Search PubMed titles/abstracts | rolitetracycline |
UniChem Compound Search for chemical match using the InChIKey | HMEYVGGHISAPJR-IAHYZSEUSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | HMEYVGGHISAPJR-IAHYZSEUSA-N |