hydralazine   Click here for help

GtoPdb Ligand ID: 7326

Synonyms: Apresoline®
Approved drug PDB Ligand
hydralazine is an approved drug (FDA (1953))
Compound class: Synthetic organic
Comment: Hydralazine is a hydrazinophthalazine class anti-hypertensiove drug.
Hydralazine is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 67.06
Molecular weight 160.07
XLogP 1.58
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES NN=c1[nH]ncc2c1cccc2
Isomeric SMILES NN=c1[nH]ncc2c1cccc2
InChI InChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)
InChI Key RPTUSVTUFVMDQK-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1953))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name Click here for help
1-hydrazinylidene-1,2-dihydrophthalazine
International Nonproprietary Names Click here for help
INN number INN
1 hydralazine
Synonyms Click here for help
Apresoline®
Database Links Click here for help
CAS Registry No. 86-54-4
ChEMBL Ligand CHEMBL276832
DrugBank Ligand DB01275
DrugCentral Ligand 1384
GtoPdb PubChem SID 178103898
PubChem CID 3637
RCSB PDB Ligand HLZ
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Wikipedia Hydralazine