hydralazine

Ligand id: 7326

Name: hydralazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 67.06
Molecular weight 160.07
XLogP 1.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1953))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
1-hydrazinylidene-1,2-dihydrophthalazine
International Nonproprietary Names
INN number INN
1 hydralazine
Synonyms
Apresoline®
Comments
Hydralazine is a hydrazinophthalazine class anti-hypertensiove drug.
Hydralazine is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Database Links
CAS Registry No. 86-54-4
ChEMBL Ligand CHEMBL276832
DrugBank Ligand DB01275
GtoPdb PubChem SID 178103898
PubChem CID 3637
RCSB PDB Ligand HLZ
Search Google for chemical match using the InChIKey RPTUSVTUFVMDQK-UHFFFAOYSA-N
Search Google for chemicals with the same backbone RPTUSVTUFVMDQK
Search PubMed clinical trials hydralazine
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Search UniChem for chemical match using the InChIKey RPTUSVTUFVMDQK-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone RPTUSVTUFVMDQK
Wikipedia Hydralazine