mirabegron [Ligand Id: 7445] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL2095212 (Betanis, Betmiga, Mirabegron, Myrbetriq, Myrbetriq granules, YM-178, YM178) |
|---|
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588] | ||||||||
| GtoPdb | - | - | 5 | pEC50 | - | - | - |
J Pharmacol Exp Ther (2007) 321: 642-7 [PMID:17293563]; Pharmacol Res Perspect (2020) 8: e00643 [PMID:32813332] |
| β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550] | ||||||||
| GtoPdb | - | - | 5 | pEC50 | >10000 | nM | EC50 | J Pharmacol Exp Ther (2007) 321: 642-7 [PMID:17293563] |
| GtoPdb | - | - | 5.2 | pEC50 | - | - | - |
J Pharmacol Exp Ther (2007) 321: 642-7 [PMID:17293563]; Pharmacol Res Perspect (2020) 8: e00643 [PMID:32813332] |
| β2-adrenoceptor in Rat [GtoPdb: 29] [UniProtKB: P10608] | ||||||||
| GtoPdb | - | - | 5 | pEC50 | - | - | - | Pharmacol Res Perspect (2020) 8: e00643 [PMID:32813332] |
| β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945] | ||||||||
| GtoPdb | - | - | 8.8 | pEC50 | - | - | - |
J Pharmacol Exp Ther (2007) 321: 642-7 [PMID:17293563]; Curr Ther Res Clin Exp (2022) 96: 100674 [PMID:35693456]; Pharmacol Res Perspect (2020) 8: e00643 [PMID:32813332]; Naunyn Schmiedebergs Arch Pharmacol (2013) 386: 247-53 [PMID:23239087] |
| β3-adrenoceptor in Mouse [GtoPdb: 30] [UniProtKB: P25962] | ||||||||
| GtoPdb | - | - | 7.8 | pEC50 | - | - | - | Pharmacol Res Perspect (2020) 8: e00643 [PMID:32813332] |
| GtoPdb | - | - | 9.3 | pEC50 | - | - | - | Pharmacol Res Perspect (2020) 8: e00643 [PMID:32813332] |
| β3-adrenoceptor in Rat [GtoPdb: 30] [UniProtKB: P26255] | ||||||||
| GtoPdb | - | - | 7.7 | pEC50 | - | - | - | Pharmacol Res Perspect (2020) 8: e00643 [PMID:32813332] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
