compound 52 [PMID: 28541707] [Ligand Id: 10001] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336] | ||||||||
| GtoPdb | Calculated based on 700-fold lower than affinity for PI3Kδ. | - | 5.92 | pIC50 | 1190 | nM | IC50 | J Med Chem (2017) 60: 5193-5208 [PMID:28541707] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329] | ||||||||
| GtoPdb | - | - | 8.77 | pIC50 | 1.7 | nM | IC50 | J Med Chem (2017) 60: 5193-5208 [PMID:28541707] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736] | ||||||||
| GtoPdb | Calculated based on potency being 100-fold lower for PI3Kγ than for PI3Kδ. | - | 6.77 | pIC50 | 170 | nM | IC50 | J Med Chem (2017) 60: 5193-5208 [PMID:28541707] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
