FP0429 [Ligand Id: 1409] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL212233 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| mGlu4 receptor in Human [GtoPdb: 292] [UniProtKB: Q14833] | ||||||||
| GtoPdb | - | - | 7.4 | pEC50 | - | - | - | Mol Pharmacol (2007) 71: 704-12 [PMID:17167031] |
| mGlu4 receptor/Metabotropic glutamate receptor 4 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2787] [GtoPdb: 292] [UniProtKB: P31423] | ||||||||
| ChEMBL | Activity at rat mGluR4 receptor measured as intracellular calcium concentration in HEK293 cells | F | 4.32 | pEC50 | 48300 | nM | EC50 | Bioorg Med Chem Lett (2006) 16: 4856-4860 [PMID:16828551] |
| mGlu8 receptor/Metabotropic glutamate receptor 8 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2718] [GtoPdb: 296] [UniProtKB: P70579] | ||||||||
| ChEMBL | Activity at rat mGluR8 receptor measured as intracellular calcium concentration in HEK293 cells | F | 4.25 | pEC50 | 56200 | nM | EC50 | Bioorg Med Chem Lett (2006) 16: 4856-4860 [PMID:16828551] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
