NU-7026   Click here for help

GtoPdb Ligand ID: 5959

Synonyms: DNA-PK inhibitor II | LY-293646 | NU 7026 | NU7026
Compound class: Synthetic organic
Comment: NU-7026 is a potent and selective, ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK) [5].
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 42.68
Molecular weight 281.11
XLogP 4.29
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES O=c1cc(oc2c1ccc1c2cccc1)N1CCOCC1
Isomeric SMILES O=c1cc(oc2c1ccc1c2cccc1)N1CCOCC1
InChI InChI=1S/C17H15NO3/c19-15-11-16(18-7-9-20-10-8-18)21-17-13-4-2-1-3-12(13)5-6-14(15)17/h1-6,11H,7-10H2
InChI Key KKTZALUTXUZPSN-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
2-(morpholin-4-yl)-4H-benzo[h]chromen-4-one
Synonyms Click here for help
DNA-PK inhibitor II | LY-293646 | NU 7026 | NU7026
Database Links Click here for help
CAS Registry No. 154447-35-5
ChEMBL Ligand CHEMBL104468
GtoPdb PubChem SID 178102582
PubChem CID 9860529
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Tocris
NU 7026
Cat. No. 2828