phenoxybenzamine   Click here for help

GtoPdb Ligand ID: 7268

Synonyms: Dibenzyline® | phenoxybenzamine hydrochloride
Approved drug
phenoxybenzamine is an approved drug (FDA (1953))
Compound class: Synthetic organic
Comment: Phenoxybenzamine is a non-selective, irreversible alpha blocker (α-adrenoceptor antagonist).
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 8
Topological polar surface area 12.47
Molecular weight 303.14
XLogP 4.72
No. Lipinski's rules broken 0
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Canonical SMILES ClCCN(C(COc1ccccc1)C)Cc1ccccc1
Isomeric SMILES ClCCN(C(COc1ccccc1)C)Cc1ccccc1
InChI InChI=1S/C18H22ClNO/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17/h2-11,16H,12-15H2,1H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1953))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
608 phenoxybenzamine
Synonyms Click here for help
Dibenzyline® | phenoxybenzamine hydrochloride
Database Links Click here for help
Specialist databases
GPCRdb Ligand phenoxybenzamine
Other databases
CAS Registry No. 59-96-1
DrugBank Ligand DB00925
DrugCentral Ligand 2136
GtoPdb PubChem SID 178103842
PubChem CID 4768
Search Google for chemical match using the InChIKey QZVCTJOXCFMACW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone QZVCTJOXCFMACW
Search PubMed clinical trials phenoxybenzamine
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UniChem Compound Search for chemical match using the InChIKey QZVCTJOXCFMACW-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey QZVCTJOXCFMACW-UHFFFAOYSA-N
Wikipedia Phenoxybenzamine