compound 22 [PMID: 19899765] [Ligand Id: 6562] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL571153
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Endothelin-converting enzyme 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4791] [GtoPdb: 1615] [UniProtKB: P42892]
GtoPdb - - 5.92 pKi 1200 nM Ki J Med Chem (2010) 53: 208-20 [PMID:19899765]
ChEMBL Inhibition of human somatic ECE1 B 8.92 pKi 1.2 nM Ki J. Med. Chem. (2010) 53: 208-220 [PMID:19899765]
Neutral endopeptidase/Neprilysin in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1944] [GtoPdb: 1611] [UniProtKB: P08473]
ChEMBL Inhibition of human somatic NEP B 8.85 pKi 1.4 nM Ki J. Med. Chem. (2010) 53: 208-220 [PMID:19899765]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]