neuromedin B [Ligand Id: 613] activity data from GtoPdb

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  • BB1 receptor in Human [GtoPdb: 38] [UniProtKB: P28336]
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  • BB2 receptor in Human [GtoPdb: 39] [UniProtKB: P30550]
  • BB2 receptor in Mouse [GtoPdb: 39] [UniProtKB: P21729]
  • BB2 receptor in Rat [GtoPdb: 39] [UniProtKB: P52500]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
BB1 receptor in Human [GtoPdb: 38] [UniProtKB: P28336]
GtoPdb - - 10.3 pKi 0.05 nM Ki Pharmacol Rev (2008) 60: 1-42 [PMID:18055507];
Peptides (2011) 32: 1685-99 [PMID:21729729];
Peptides (2015) 72: 128-44 [PMID:25976083]
BB2 receptor in Human [GtoPdb: 39] [UniProtKB: P30550]
GtoPdb - - 8.13 pKi 7.4 nM Ki J Pharmacol Exp Ther (1999) 290: 1202-11 [PMID:10454496];
Mol Pharmacol (1995) 47: 10-20 [PMID:7838118]
GtoPdb - - 7.52 pIC50 30.1 nM IC50 Peptides (2011) 32: 1685-99 [PMID:21729729];
Peptides (2009) 30: 1473-86 [PMID:19463875]
BB2 receptor in Mouse [GtoPdb: 39] [UniProtKB: P21729]
GtoPdb - - 7.38 pKi 42 nM Ki Mol Pharmacol (1995) 47: 10-20 [PMID:7838118]
BB2 receptor in Rat [GtoPdb: 39] [UniProtKB: P52500]
GtoPdb - - 6.61 pKi 248 nM Ki J Pharmacol Exp Ther (1999) 290: 1202-11 [PMID:10454496]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.