compound 18 [PMID: 15664838] [Ligand Id: 6536] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL367368
  • Dipeptidyl-peptidase 7/Dipeptidyl peptidase II in Human [ChEMBL: CHEMBL3976] [GtoPdb: 1605] [UniProtKB: Q9UHL4]
There should be some charts here, you may need to enable JavaScript!
  • Dipeptidyl peptidase IV in Porphyromonas gingivalis [ChEMBL: CHEMBL4295559] [UniProtKB: O31048]
  • dipeptidyl peptidase 4/Dipeptidyl peptidase IV in Human [ChEMBL: CHEMBL284] [GtoPdb: 1612] [UniProtKB: P27487]
There should be some charts here, you may need to enable JavaScript!
  • dipeptidyl peptidase 8/Dipeptidyl peptidase VIII in Human [ChEMBL: CHEMBL4657] [GtoPdb: 2356] [UniProtKB: Q6V1X1]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Dipeptidyl-peptidase 7/Dipeptidyl peptidase II in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3976] [GtoPdb: 1605] [UniProtKB: Q9UHL4]
ChEMBL Inhibitory concentration against dipeptidylpeptidase 2 B 4.42 pIC50 38377 nM IC50 Bioorg. Med. Chem. Lett. (2005) 15: 687-691 [PMID:15664838]
Dipeptidyl peptidase IV in Porphyromonas gingivalis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4295559] [UniProtKB: O31048]
ChEMBL Inhibition of Porphyromonas gingivalis N-terminal His-tagged DPP4 expressed in Escherichia coli using Gly-Pro-p-nitroanilide as substrate B 5 pIC50 10000 nM IC50 Eur J Med Chem (2017) 139: 482-491 [PMID:28826083]
dipeptidyl peptidase 4/Dipeptidyl peptidase IV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL284] [GtoPdb: 1612] [UniProtKB: P27487]
ChEMBL Inhibitory concentration against dipeptidylpeptidase IV B 4 pIC50 >100000 nM IC50 Bioorg. Med. Chem. Lett. (2005) 15: 687-691 [PMID:15664838]
dipeptidyl peptidase 8/Dipeptidyl peptidase VIII in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4657] [GtoPdb: 2356] [UniProtKB: Q6V1X1]
ChEMBL Inhibitory concentration against dipeptidylpeptidase 8 B 7.85 pIC50 14 nM IC50 Bioorg. Med. Chem. Lett. (2005) 15: 687-691 [PMID:15664838]
GtoPdb - - 7.9 pIC50 14 nM IC50 Bioorg Med Chem Lett (2005) 15: 687-91 [PMID:15664838]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]