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Dipeptidyl-peptidase 7

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Target not currently curated in GtoImmuPdb

Target id: 1605

Nomenclature: Dipeptidyl-peptidase 7

Family: S28: Lysosomal Pro-Xaa carboxypeptidase

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 492 9q34.3 DPP7 dipeptidyl peptidase 7
Mouse - 506 2 A3 Dpp7 dipeptidylpeptidase 7
Rat - 500 3p13 Dpp7 dipeptidylpeptidase 7
Previous and Unofficial Names Click here for help
DPPII | dipeptidyl aminopeptidase II | dipeptidyl peptidase 2 | dipeptidyl peptidase II | Dpp2 | quiescent cell proline dipeptidase | QPP | dipeptidyl-peptidase 7
Database Links Click here for help
Specialist databases
MEROPS S28.002 (Hs)
Other databases
Alphafold
BRENDA
CATH/Gene3D
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
KEGG Gene
OMIM
Pharos
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Enzyme Reaction Click here for help
EC Number: 3.4.14.2

Download all structure-activity data for this target as a CSV file go icon to follow link

Inhibitors
Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
UAMC00039 Small molecule or natural product Hs Inhibition 10.1 pKi 1
pKi 10.1 (Ki 8.2x10-11 M) [1]
Immuno Process Associations
Immuno Process:  Inflammation
Immuno Process:  Cellular signalling

References

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1. Maes MB, Martinet W, Schrijvers DM, Van der Veken P, De Meyer GR, Augustyns K, Lambeir AM, Scharpé S, De Meester I. (2006) Dipeptidyl peptidase II and leukocyte cell death. Biochem Pharmacol, 72 (1): 70-9. [PMID:16725115]

How to cite this page

S28: Lysosomal Pro-Xaa carboxypeptidase: Dipeptidyl-peptidase 7. Last modified on 21/11/2013. Accessed on 04/12/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1605.