hIMB1636-MMAE   Click here for help

GtoPdb Ligand ID: 12978

Compound class: Antibody
Comment: hIMB1636-MMAE is an anti-TROP2 antibody-drug conjugate [1]. It binds to TROP2 on cancer cells and induces their death by apoptosis, ADCC and bystander effects. The MMAE (monomethyl auristatin E; a.k.a. vedotin) conjugate is a widely used microtubule disrupting agent that is liberated once the ADC is internalised by target cells. The PubChem ID for MMAE is CID 11542188.
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Classification Click here for help
Compound class Antibody
Database Links Click here for help
GtoPdb PubChem SID 485206099