ChEMBL ligand: CHEMBL418353
CB1 receptor/Cannabinoid CB1 receptor in Rat [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272] There should be some charts here, you may need to enable JavaScript!
CB2 receptor/Cannabinoid CB2 receptor in Mouse [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936] CB2 receptor/Cannabinoid CB2 receptor in Rat [ChEMBL: CHEMBL2470] [GtoPdb: 57] [UniProtKB: Q9QZN9] There should be some charts here, you may need to enable JavaScript!
GPR18 in Human [GtoPdb: 89] [UniProtKB: Q14330] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
CB1 receptor/Cannabinoid CB1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
ChEMBL	Binding affinity towards rat brain cannabinoid receptor 1 in the presence of PMSF upon incubation for 15 min at 4 degree C in pH 7.4 using [3H]CP-55940	B	8.57	pKi	2.7	nM	Ki	J. Med. Chem. (2005) 48: 6423-6429 [PMID:16190768]
ChEMBL	Displacement of [3H]-CP55940 from CB1 receptor of rat cerebellar membranes by liquid scintillation counting in presence of serine protease inhibitor PMSF	B	8.66	pKi	2.2	nM	Ki	J. Med. Chem. (2013) 56: 8224-8256 [PMID:23865723]
GtoPdb	-	-	8.7	pKi	-	-	-	J Pharmacol Exp Ther (1999) 289: 1427-33 [PMID:10336536]
ChEMBL	Displacement of [35S]GTP-gamma-S from rat cerebellar CB1 receptor	F	6.4	pEC50	398.11	nM	EC50	J. Med. Chem. (2006) 49: 554-566 [PMID:16420041]
CB2 receptor/Cannabinoid CB2 receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936]
ChEMBL	Binding affinity towards mouse spleen cannabinoid receptor 2 in the presence of PMSF upon incubation for 15 min at 4 degree C in pH 7.4 using [3H]CP-55940	B	6.8	pKi	157	nM	Ki	J. Med. Chem. (2005) 48: 6423-6429 [PMID:16190768]
CB2 receptor/Cannabinoid CB2 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2470] [GtoPdb: 57] [UniProtKB: Q9QZN9]
ChEMBL	Displacement of [3H]-CP55940 from CB2 receptor of rat spleen membranes by liquid scintillation counting in presence of serine protease inhibitor PMSF	B	6.15	pKi	715	nM	Ki	J. Med. Chem. (2013) 56: 8224-8256 [PMID:23865723]
GPR18 in Human [GtoPdb: 89] [UniProtKB: Q14330]
GtoPdb	-	-	4.87	pEC50	13500	nM	EC50	Br J Pharmacol (2012) 165: 2414-24 [PMID:21595653]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]