cefpirome   Click here for help

GtoPdb Ligand ID: 12033

Synonyms: HR 810 | Romecef®
Approved drug
cefpirome is an approved drug (Thailand (2016))
Compound class: Synthetic organic
Comment: Cefpirome is a semisynthetic, fourth generation cephalosporin belonging to the β-lactam class of antibacterial compounds [1].
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 207.46
Molecular weight 514.11
XLogP -0.85
No. Lipinski's rules broken 0
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Canonical SMILES CO/N=C(\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])C[n+]1cccc2c1CCC2)/c1csc(n1)N
Isomeric SMILES CO/N=C(/c1csc(n1)N)\C(=O)N[C@H]1[C@@H]2N(C1=O)C(=C(CS2)C[n+]1cccc2c1CCC2)C(=O)[O-]
InChI InChI=1S/C22H22N6O5S2/c1-33-26-15(13-10-35-22(23)24-13)18(29)25-16-19(30)28-17(21(31)32)12(9-34-20(16)28)8-27-7-3-5-11-4-2-6-14(11)27/h3,5,7,10,16,20H,2,4,6,8-9H2,1H3,(H3-,23,24,25,29,31,32)/b26-15-/t16-,20-/m1/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (Thailand (2016))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
5414 cefpirome
Synonyms Click here for help
HR 810 | Romecef®
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Cefpirome
Other databases
CAS Registry No. 84957-29-9 (source: Scifinder)
ChEMBL Ligand CHEMBL65794
DrugBank Ligand DB13682
DrugCentral Ligand 553
GtoPdb PubChem SID 464244174
PubChem CID 5479539
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UniChem Compound Search for chemical match using the InChIKey DKOQGJHPHLTOJR-WHRDSVKCSA-N
UniChem Connectivity Search for chemical match using the InChIKey DKOQGJHPHLTOJR-WHRDSVKCSA-N