AT-9283 [Ligand Id: 7949] activity data from GtoPdb

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  • ribosomal protein S6 kinase A6 in Human [GtoPdb: 1530] [UniProtKB: Q9UK32]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 ribosomal protein S6 kinase A6 Human
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  • aurora kinase A in Human [GtoPdb: 1936] [UniProtKB: O14965]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 aurora kinase A Human
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  • aurora kinase B in Human [GtoPdb: 1937] [UniProtKB: Q96GD4]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 aurora kinase B Human
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  • Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 Janus kinase 2 Human
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  • Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
  • This target only has 0 pki data point
  • 0
5 _lig_chart_5 Janus kinase 3 Human
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  • serine/threonine kinase 17a in Human [GtoPdb: 2214] [UniProtKB: Q9UEE5]
  • This target only has 0 pki data point
  • 0
6 _lig_chart_6 serine/threonine kinase 17a Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ribosomal protein S6 kinase A6 in Human [GtoPdb: 1530] [UniProtKB: Q9UK32]
GtoPdb - - 8 pIC50 10 nM IC50 J Med Chem (2009) 52: 379-88 [PMID:19143567]
aurora kinase A in Human [GtoPdb: 1936] [UniProtKB: O14965]
GtoPdb - - 8.52 pIC50 ~3 nM IC50 J Med Chem (2009) 52: 379-88 [PMID:19143567]
aurora kinase B in Human [GtoPdb: 1937] [UniProtKB: Q96GD4]
GtoPdb - - 8.52 pIC50 ~3 nM IC50 J Med Chem (2009) 52: 379-88 [PMID:19143567]
Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
GtoPdb - - 8.92 pIC50 1.2 nM IC50 J Med Chem (2009) 52: 379-88 [PMID:19143567]
Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
GtoPdb - - 8.96 pIC50 1.1 nM IC50 J Med Chem (2009) 52: 379-88 [PMID:19143567]
serine/threonine kinase 17a in Human [GtoPdb: 2214] [UniProtKB: Q9UEE5]
GtoPdb - - 8 pIC50 10 nM IC50 J Med Chem (2009) 52: 379-88 [PMID:19143567]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.