Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL20921 |
---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
CCR1/C-C chemokine receptor type 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2413] [GtoPdb: 58] [UniProtKB: P32246] | ||||||||
ChEMBL | Concentration required for 50% inhibition of [125I]eotaxin binding to human CCR1 receptor expressed in CHO cells | B | 5.72 | pIC50 | 1900 | nM | IC50 | Bioorg. Med. Chem. Lett. (2001) 11: 1219-1223 [PMID:11354381] |
CCR3/C-C chemokine receptor type 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3473] [GtoPdb: 60] [UniProtKB: P51677] | ||||||||
GtoPdb | - | - | 8.3 | pKd | - | - | - | Eur J Pharmacol (2002) 456: 1-10 [PMID:12450563] |
ChEMBL | Binding affinity was determined towards C-C chemokine receptor type 3 using [125I]-labeled eotaxin as radioligand | B | 8.64 | pIC50 | 2.3 | nM | IC50 | Bioorg. Med. Chem. Lett. (2003) 13: 3597-3600 [PMID:14505678] |
ChEMBL | Concentration required for 50% inhibition of [125I]eotaxin binding to human CCR3 receptor expressed in CHO cells | B | 8.64 | pIC50 | 2.3 | nM | IC50 | Bioorg. Med. Chem. Lett. (2001) 11: 1219-1223 [PMID:11354381] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]