[3H]banyu (I) [Ligand Id: 795] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL20921 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CCR1/C-C chemokine receptor type 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2413] [GtoPdb: 58] [UniProtKB: P32246] | ||||||||
| ChEMBL | Concentration required for 50% inhibition of [125I]eotaxin binding to human CCR1 receptor expressed in CHO cells | B | 5.72 | pIC50 | 1900 | nM | IC50 | Bioorg Med Chem Lett (2001) 11: 1219-1223 [PMID:11354381] |
| CCR3/C-C chemokine receptor type 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3473] [GtoPdb: 60] [UniProtKB: P51677] | ||||||||
| GtoPdb | - | - | 8.3 | pKd | - | - | - | Eur J Pharmacol (2002) 456: 1-10 [PMID:12450563] |
| ChEMBL | Binding affinity was determined towards C-C chemokine receptor type 3 using [125I]-labeled eotaxin as radioligand | B | 8.64 | pIC50 | 2.3 | nM | IC50 | Bioorg Med Chem Lett (2003) 13: 3597-3600 [PMID:14505678] |
| ChEMBL | Concentration required for 50% inhibition of [125I]eotaxin binding to human CCR3 receptor expressed in CHO cells | B | 8.64 | pIC50 | 2.3 | nM | IC50 | Bioorg Med Chem Lett (2001) 11: 1219-1223 [PMID:11354381] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
