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ChEMBL ligand: CHEMBL29078 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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δ receptor in Human [GtoPdb: 317] [UniProtKB: P41143] | ||||||||
GtoPdb | - | - | 8.8 | pKi | - | - | - | NIDA Res Monogr (1998) 178: 440-66 [PMID:9686407] |
δ receptor/Delta opioid receptor in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3222] [GtoPdb: 317] [UniProtKB: P32300] | ||||||||
GtoPdb | - | - | 8.5 | pKi | - | - | - | Mol Pharmacol (1994) 45: 330-4 [PMID:8114680] |
ChEMBL | In vitro opioid receptor delta mediated mouse vas deferens (MVD) assay | B | 9.12 | pIC50 | 0.75 | nM | IC50 | J Med Chem (1991) 34: 1656-1661 [PMID:1851843] |
δ receptor/Delta opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL269] [GtoPdb: 317] [UniProtKB: P33533] | ||||||||
ChEMBL | Displacement of [3H]DSLET from delta opioid receptor in rat brain membrane | B | 8.42 | pIC50 | 3.8 | nM | IC50 | J Med Chem (1991) 34: 1656-1661 [PMID:1851843] |
ChEMBL | Displacement of [3H]- DPDPE from delta opioid receptor in rat brain membrane | B | 8.44 | pIC50 | 3.6 | nM | IC50 | J Med Chem (1991) 34: 1656-1661 [PMID:1851843] |
μ receptor/Mu opioid receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL270] [GtoPdb: 319] [UniProtKB: P33535] | ||||||||
ChEMBL | Displacement of [3H]- DAGO from opioid receptor mu in rat brain membrane | B | 5.49 | pIC50 | 3200 | nM | IC50 | J Med Chem (1991) 34: 1656-1661 [PMID:1851843] |
Mu opioid receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4354] [UniProtKB: P97266] | ||||||||
ChEMBL | Inhibition of opioid receptor mu in guinea pig ileum (GPI) | B | 5.28 | pIC50 | 5200 | nM | IC50 | J Med Chem (1991) 34: 1656-1661 [PMID:1851843] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]