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1
_lig_chart_1
TRPA1
Mouse
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2
_lig_chart_2
TRPC3
Human
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3
_lig_chart_3
TRPC6
Mouse
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4
_lig_chart_4
TRPM3
Human
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5
_lig_chart_5
TRPML3
Mouse
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6
_lig_chart_6
ASIC3
Human
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7
_lig_chart_7
Navi2.1
Human
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8] | ||||||||
GtoPdb | - | - | 7 | pIC50 | - | - | - | J Neurosci (2005) 25: 4052-61 [PMID:15843607] |
TRPC3 in Human [GtoPdb: 488] [UniProtKB: Q13507] | ||||||||
GtoPdb | - | - | 7 | pEC50 | 100 | nM | EC50 | J Biol Chem (2000) 275: 37423-8 [PMID:10970899] |
TRPC6 in Mouse [GtoPdb: 491] [UniProtKB: Q61143] | ||||||||
GtoPdb | - | - | 5.7 | pIC50 | 1900 | nM | IC50 | Circ Res (2001) 88: 325-32 [PMID:11179201] |
TRPM3 in Human [GtoPdb: 495] [UniProtKB: Q9HCF6] | ||||||||
GtoPdb | - | - | 4 | pIC50 | - | - | - |
J Biol Chem (2003) 278: 20890-7 [PMID:12672827]; J Biol Chem (2003) 278: 21493-501 [PMID:12672799] |
TRPML3 in Mouse [GtoPdb: 503] [UniProtKB: Q8R4F0] | ||||||||
GtoPdb | - | - | 4.7 | pIC50 | 20000 | nM | IC50 | Proc Natl Acad Sci USA (2008) 105: 353-8 [PMID:18162548] |
ASIC3 in Human [GtoPdb: 686] [UniProtKB: Q9UHC3] | ||||||||
GtoPdb | - | - | 4.4 | pIC50 | 40000 | nM | IC50 | J Biol Chem (2000) 275: 28519-25 [PMID:10842183] |
Navi2.1 in Human [GtoPdb: 750] [UniProtKB: Q8IZF0] | ||||||||
GtoPdb | - | - | 5.6 | pIC50 | 1400 | nM | IC50 |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.