SC46275 [Ligand Id: 3331] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL49922 (SC-46275) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| EP3 receptor in Dog [GtoPdb: 342] | ||||||||
| GtoPdb | - | - | 11 | pIC50 | 0.01 | nM | IC50 | J Pharmacol Exp Ther (1995) 275: 368-73 [PMID:7562572] |
| EP3 receptor in Rat [GtoPdb: 342] [UniProtKB: P34980] | ||||||||
| GtoPdb | - | - | 8.74 | pEC50 | 1.8 | nM | EC50 | Prostaglandins Leukot Essent Fatty Acids (2006) 74: 401-15 [PMID:16737803] |
| EP3 receptor in Guinea pig [GtoPdb: 342] | ||||||||
| GtoPdb | - | - | 10.4 | pEC50 | 0.04 | nM | EC50 | Prostaglandins Leukot Essent Fatty Acids (1993) 49: 939-43 [PMID:8140121] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
