cinromide [Ligand Id: 10256] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL93233 (3-bromo-n-ethylcinnamamide, trans, Cinromida, Cinromide, NSC-335304) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| B0AT1/Sodium-dependent neutral amino acid transporter B(0)AT1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5724588] [GtoPdb: 939] [UniProtKB: Q695T7] | ||||||||
| ChEMBL | Affinity On-target Cellular interaction: (Detection of membrane depolarisation induced by amino acid transport using a FLIPR kit, CHO-BC cells) EUB0002537a SLC6A19 | F | 6.3 | pIC50 | 500 | nM | IC50 | Affinity On-target Cellular Literature for EUbOPEN Chemogenomic Library |
| GtoPdb | - | - | 6.4 | pIC50 | - | - | - | SLAS Discov (2019) 24: 111-120 [PMID:30589598] |
| ChEMBL | Affinity On-target Cellular interaction: (Stable isotope uptake assay, MDCK cells) EUB0002537a SLC6A19 | F | 6.43 | pIC50 | 370 | nM | IC50 | Affinity On-target Cellular Literature for EUbOPEN Chemogenomic Library |
| ChEMBL | Affinity On-target Cellular interaction: (Fluorescence imaging plate reader (FLIPR) membrane potential (FMP) assay, MDCK cells) EUB0002537a SLC6A19 | F | 6.55 | pIC50 | 280 | nM | IC50 | Affinity On-target Cellular Literature for EUbOPEN Chemogenomic Library |
ChEMBL data shown on this page come from version 36:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
