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Synonyms: D2E7  | Humira®
adalimumab is an approved drug (FDA (2002), EMA (2003))
Compound class: Antibody
Comment: Adalimumab is an anti-TNFα monoclonal antibody with immunosuppresive activity . It was the first fully human monoclonal antibody drug approved by the FDA.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
X-ray structures of the apo and TNFα-bound Fab fragment of adalimumab have been deposited to the RCSB Protein Data Bank (IDs 4NYL and 3WD5 respectively).
View more information in the IUPHAR Pharmacology Education Project: adalimumab
|Approved drug?||Yes (FDA (2002), EMA (2003))|
|WHO Essential Medicine||WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.|
|International Nonproprietary Names|
|D2E7  | Humira®|
|GtoPdb PubChem SID||178101561|
|Search PubMed clinical trials||adalimumab|
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|Search PubMed titles/abstracts||adalimumab|