hK2p01 derivative KLK2 inhibitor [Ligand Id: 8672] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2171880 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| kallikrein related peptidase 2/Kallikrein 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2442] [GtoPdb: 2372] [UniProtKB: P20151] | ||||||||
| GtoPdb | - | - | 5.85 | pKi | 1410 | nM | Ki | J Biol Chem (2006) 281: 12555-60 [PMID:16527822] |
| ChEMBL | Inhibition of human KLK2 after 1 hr by phage-display based Immunofluorometric Assay | B | 5.85 | pKi | 1410 | nM | Ki | J Med Chem (2012) 55: 6669-6686 [PMID:22607152] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
