IL-1 receptor antagonist   Click here for help

GtoPdb Ligand ID: 5878

Synonyms: IL-1ra | interleukin-1 receptor antagonist protein | IRAP
Immunopharmacology Ligand
Comment: A recombinant, non-glycosylated version of this protein is marketed as rheumatoid arthritis drug anakinra.
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interleukins
Synonyms Click here for help
IL-1ra | interleukin-1 receptor antagonist protein | IRAP
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
IL1RN interleukin 1 receptor antagonist Human prepro-interleukin-1 receptor antagonist protein ICIL-1RA, IL1F3, IL1RA, IL-1RN, interleukin-1 receptor antagonist protein, intracellular interleukin-1 receptor antagonist, IRAP, MGC10430
Database Links Click here for help
Ensembl Gene ENSG00000136689 (Hs)
GtoPdb PubChem SID 178102502
Human Protein Atlas ENSG00000136689 (Hs)
SynPHARM 77163 (in complex with Interleukin-1 receptor, type I)
UniProtKB P18510 (Hs)
Wikipedia IL1RN