brensocatib [Ligand Id: 9412] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| cathepsin C in Human [GtoPdb: 2344] [UniProtKB: P53634] | ||||||||
| GtoPdb | Surface plasmon resonance direct binding assay | - | 8.6 | pKd | 2.5 | nM | Kd | J Med Chem (2016) 59: 9457-9472 [PMID:27690432] |
| GtoPdb | In vitro enzyme assay | - | 8.4 | pIC50 | 3.98 | nM | IC50 | J Med Chem (2016) 59: 9457-9472 [PMID:27690432] |
| cathepsin C in Mouse [GtoPdb: 2344] [UniProtKB: P97821] | ||||||||
| GtoPdb | In vitro enzyme assay | - | 7.6 | pIC50 | 25.1 | nM | IC50 | J Med Chem (2016) 59: 9457-9472 [PMID:27690432] |
| cathepsin C in Rat [GtoPdb: 2344] [UniProtKB: P80067] | ||||||||
| GtoPdb | In vitro enzyme assay | - | 7.7 | pIC50 | 19.9 | nM | IC50 | J Med Chem (2016) 59: 9457-9472 [PMID:27690432] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
