[3H]iloprost [Ligand Id: 1966] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1628635
  • IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119]
  • IP receptor in Mouse [GtoPdb: 345] [UniProtKB: P43252]
  • IP receptor in Rat [GtoPdb: 345] [UniProtKB: P43253]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119]
GtoPdb - - 9 pKd 1 nM Kd Br J Pharmacol (2006) 148: 326-39 [PMID:16604093];
Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944];
J Biol Chem (1994) 269: 12173-8 [PMID:7512962];
Biochem Pharmacol (2012) 84: 68-75 [PMID:22480736]
IP receptor in Mouse [GtoPdb: 345] [UniProtKB: P43252]
GtoPdb - - 8.3 pKd - - - J Biol Chem (1994) 269: 9986-92 [PMID:7511597]
IP receptor in Rat [GtoPdb: 345] [UniProtKB: P43253]
GtoPdb - - 8.9 pKd - - - Biochim Biophys Acta (1994) 1224: 601-5 [PMID:7803522]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]