banyu (I) [Ligand Id: 796] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL20921
  • CCR1/C-C chemokine receptor type 1 in Human [ChEMBL: CHEMBL2413] [GtoPdb: 58] [UniProtKB: P32246]
There should be some charts here, you may need to enable JavaScript!
  • CCR3/C-C chemokine receptor type 3 in Human [ChEMBL: CHEMBL3473] [GtoPdb: 60] [UniProtKB: P51677]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CCR1/C-C chemokine receptor type 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2413] [GtoPdb: 58] [UniProtKB: P32246]
ChEMBL Concentration required for 50% inhibition of [125I]eotaxin binding to human CCR1 receptor expressed in CHO cells B 5.72 pIC50 1900 nM IC50 Bioorg Med Chem Lett (2001) 11: 1219-1223 [PMID:11354381]
CCR3/C-C chemokine receptor type 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3473] [GtoPdb: 60] [UniProtKB: P51677]
GtoPdb - - 8.5 pKi 3.16 nM Ki Eur J Pharmacol (2002) 456: 1-10 [PMID:12450563]
ChEMBL Binding affinity was determined towards C-C chemokine receptor type 3 using [125I]-labeled eotaxin as radioligand B 8.64 pIC50 2.3 nM IC50 Bioorg Med Chem Lett (2003) 13: 3597-3600 [PMID:14505678]
ChEMBL Concentration required for 50% inhibition of [125I]eotaxin binding to human CCR3 receptor expressed in CHO cells B 8.64 pIC50 2.3 nM IC50 Bioorg Med Chem Lett (2001) 11: 1219-1223 [PMID:11354381]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]