compound 20 [PMID:12127536] [Ligand Id: 8650] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL71654 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Caspase 3/Caspase-3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2334] [GtoPdb: 1619] [UniProtKB: P42574] | ||||||||
| ChEMBL | Compound was tested for its inhibition against Caspase-3 | B | 7.59 | pKi | 26 | nM | Ki | Bioorg Med Chem Lett (2002) 12: 2197-2200 [PMID:12127536] |
| granzyme B/Granzyme B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2316] [GtoPdb: 2369] [UniProtKB: P10144] | ||||||||
| GtoPdb | - | - | 8.15 | pKi | 7 | nM | Ki | Bioorg Med Chem Lett (2002) 12: 2197-200 [PMID:12127536] |
| ChEMBL | Inhibition against human granzyme B | B | 8.15 | pKi | 7 | nM | Ki | Bioorg Med Chem Lett (2002) 12: 2197-2200 [PMID:12127536] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
