pizotifen   Click here for help

GtoPdb Ligand ID: 93

Synonyms: BC-105 | pizotifan | pizotyline | sandomigran
Approved drug
pizotifen is an approved drug (UK (1998))
Compound class: Synthetic organic
Comment: Pizotifen is a benzocycloheptene-based anti-migraine drug, acting principally as an antagonist of serotonin 5-HT2A and 5-HT2C receptors.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 31.48
Molecular weight 295.14
XLogP 2.98
No. Lipinski's rules broken 0
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Canonical SMILES CN1CCC(=C2c3ccsc3CCc3c2cccc3)CC1
Isomeric SMILES CN1CCC(=C2c3ccsc3CCc3c2cccc3)CC1
InChI InChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (UK (1998))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
2693 pizotifen
Synonyms Click here for help
BC-105 | pizotifan | pizotyline | sandomigran
Database Links Click here for help
Specialist databases
GPCRdb Ligand pizotifen
Other databases
BindingDB Ligand 82088
CAS Registry No. 73391-87-4
ChEMBL Ligand CHEMBL294951
DrugCentral Ligand 2220
GtoPdb PubChem SID 135650835
PubChem CID 27400
Search Google for chemical match using the InChIKey FIADGNVRKBPQEU-UHFFFAOYSA-N
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UniChem Compound Search for chemical match using the InChIKey FIADGNVRKBPQEU-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey FIADGNVRKBPQEU-UHFFFAOYSA-N
Wikipedia Pizotifen