ChEMBL ligand: CHEMBL177880 (Pamoic Acid)
DNA polymerase beta in Human [ChEMBL: CHEMBL2392] [GtoPdb: 3231] [UniProtKB: P06746] There should be some charts here, you may need to enable JavaScript!
GPR35/G-protein coupled receptor 35 in Human [ChEMBL: CHEMBL1293267] [GtoPdb: 102] [UniProtKB: Q9HC97] GPR35 in Rat [GtoPdb: 102] [UniProtKB: Q33BM1] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
DNA polymerase beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2392] [GtoPdb: 3231] [UniProtKB: P06746]
ChEMBL	Inhibition of DNA polymerase beta (unknown origin)	B	5.05	pIC50	9000	nM	IC50	J Med Chem (2013) 56: 5182-5197 [PMID:23713606]
GPR35/G-protein coupled receptor 35 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1293267] [GtoPdb: 102] [UniProtKB: Q9HC97]
ChEMBL	Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysis	B	7.94	pKi	11.5	nM	Ki	J Med Chem (2013) 56: 7084-7099 [PMID:23888932]
ChEMBL	Agonist activity at C-terminal beta-galactosidase tagged human recombinant GPR35 expressed in CHO cells after 90 mins by beta-arrestin recruitment assay	B	5.92	pEC50	1200	nM	EC50	J Med Chem (2013) 56: 7084-7099 [PMID:23888932]
ChEMBL	Agonist activity at human GPR35 expressed in CHO-K1 cells after 90 mins by beta-arrestin 2 recruitment assay	B	6.3	pEC50	500	nM	EC50	J Med Chem (2017) 60: 362-372 [PMID:27976894]
ChEMBL	Agonist activity at human GPR35 receptor expressed in HEK293T cells co-expressing beta-arrestin2 assessed as induction of beta-arrestin2 recruitment by BRET assay	F	6.3	pEC50	500	nM	EC50	J Med Chem (2021) 64: 2634-2647 [PMID:33630609]
GtoPdb	-	-	7.29	pEC50	-	-	-	Biochem J (2010) 432: 451-9 [PMID:20919992]
ChEMBL	Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporter gene assay	B	7.3	pEC50	50	nM	EC50	J Med Chem (2013) 56: 5182-5197 [PMID:23713606]
ChEMBL	Agonist activity at human GPR35 by DMR assay	B	8.68	pEC50	2.1	nM	EC50	J Med Chem (2013) 56: 7084-7099 [PMID:23888932]
ChEMBL	Agonist activity at human GPR35 expressed in CHO-K1 cells by DMR assay	B	8.7	pEC50	2	nM	EC50	J Med Chem (2017) 60: 362-372 [PMID:27976894]
ChEMBL	Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as dynamic mass redistribution response measured for 60 mins by DMR assay	F	8.7	pEC50	2	nM	EC50	J Med Chem (2021) 64: 2634-2647 [PMID:33630609]
GPR35 in Rat [GtoPdb: 102] [UniProtKB: Q33BM1]
GtoPdb	-	-	5	pEC50	-	-	-	Biochem J (2010) 432: 451-9 [PMID:20919992]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]