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PTH   Click here for help

GtoPdb Ligand ID: 1785

Synonyms: Natpar® | Natpara® | rhPTH[1-84]
Approved drug
PTH is an approved drug (FDA (2015), EMA (2017))
Compound class: Endogenous peptide in human, mouse or rat
Comment: In its recombinant form, human parathyroid hormone was approved for clinical use in 2015, under the name Natpara.
The amino acid sequence provided here is the mature peptide, with the signal (MIPAKDMAKVMIVMLAICFLTKSDG) and propeptide (KSVKKR) domains removed.
Species: Human
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Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Approved drug? Yes. US FDA (2015)  |  EU EMA (2017)
International Nonproprietary Names Click here for help
INN number INN
8441 parathyroid hormone
Synonyms Click here for help
Natpar® | Natpara® | rhPTH[1-84]
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
PTH parathyroid hormone Human preproparathyroid hormone (prepro-PTH) parathormone, parathyrin, parathyroid hormone 1, PTH1
Database Links Click here for help
Specialist databases
GPCRdb Ligand PTH
Other databases
CAS Registry No. 68893-82-3 (Hs)
Ensembl Gene ENSG00000152266 (Hs)
GtoPdb PubChem SID 135651867
Human Protein Atlas ENSG00000152266 (Hs)
Search PubMed clinical trials parathyroid hormone
Search PubMed titles parathyroid hormone
Search PubMed titles/abstracts parathyroid hormone
UniProtKB P01270 (Hs)
Wikipedia Parathyroid_hormone