Synonyms: Natpar® | Natpara® | rhPTH[1-84]
PTH is an approved drug (FDA (2015), EMA (2017))
Compound class:
Endogenous peptide in human, mouse or rat
Comment: In its recombinant form, human parathyroid hormone was approved for clinical use in 2015, under the name Natpara.
Species: Human
![]() View more information in the IUPHAR Pharmacology Education Project: pth |
No information available. |
Summary of Clinical Use ![]() |
Approved for use in patients with hypoparathyroidism to control low blood calcium levels. |
Mechanism Of Action and Pharmacodynamic Effects ![]() |
PTH increases levels of calcium in the blood through its interaction with the PTH1 receptor. |
External links ![]() |
For extended ADME data see the following: Drugs.com European Medicines Agency (EMA) |