Synonyms: Natpar® | Natpara® | rhPTH[1-84]
PTH is an approved drug (FDA (2015), EMA (2017))
Compound class:
Endogenous peptide in human, mouse or rat
Comment: In its recombinant form, human parathyroid hormone was approved for clinical use in 2015, under the name Natpara.
Species: Human
View more information in the IUPHAR Pharmacology Education Project: pth |
Natural/Endogenous Targets | |||
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Additional information and targets (data relate to human unless otherwise stated) | ||
Description | Data | Reference |
Potency order of endogenous ligands at PTH1 receptor | PTH (PTH, P01270) = PTHrP (PTHLH, P12272) | |
Potency order of endogenous ligands at PTH2 receptor | TIP39 (PTH2, Q96A98), PTH (PTH, P01270) >> PTHrP (PTHLH, P12272) |
Ligand mentioned in the following text fields |
Parathyroid hormone receptors overview |
Calcium-sensing receptor comments |
Parathyroid hormone receptors comments |