poseltinib [Ligand Id: 9862] activity data from GtoPdb

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  • Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
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  • Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Bruton tyrosine kinase in Human [GtoPdb: 1948] [UniProtKB: Q06187]
GtoPdb Biochemical assay result. Binned IC50 value provided in patent. - 7.3 pIC50 <50 nM IC50 WO2011162515A2. Novel fused pyrimidine derivatives for inhd3ition of tyrosine kinase activity. (2011)
Janus kinase 3 in Human [GtoPdb: 2049] [UniProtKB: P52333]
GtoPdb Biochemical assay result. Binned IC50 value provided in patent. - 7.3 pIC50 <50 nM IC50 WO2011162515A2. Novel fused pyrimidine derivatives for inhd3ition of tyrosine kinase activity. (2011)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.