opicinumab   Click here for help

GtoPdb Ligand ID: 8923

Synonyms: BIIB-033 | BIIB033
Compound class: Antibody
Comment: Opicinumab is a monoclonal antibody which acts as a functional antagonist of the neural protein, LINGO1 [2-3]. Opicinumab was investigated for its clinical utility in diseases with underlying immune-driven demyelination.
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record. A BLAST search of patented peptide sequences reveals a 100% match between the variable heavy chain region of opicinumab and SEQ ID NO: 5 from patent US8058406 B2, and another identical match between the variable light chain of the antibody and the patent's SEQ ID NO: 13 [2].
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
10090 opicinumab
Synonyms Click here for help
BIIB-033 | BIIB033
Database Links Click here for help
GtoPdb PubChem SID 310264704
Search PubMed clinical trials opicinumab
Search PubMed titles opicinumab
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