cefotaxime [Ligand Id: 10893] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1730 (Cefotaxime, Cefotaxim hikma) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| ADC-11 in Acinetobacter baumannii (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1667701] [UniProtKB: D6NSM8] | ||||||||
| ChEMBL | Activity of Acinetobacter baumannii ADC-11 beta-lactamase | B | 5.6 | pKi | 2500 | nM | Ki | Antimicrob Agents Chemother (2010) 54: 3484-3488 [PMID:20547808] |
| Beta-lactamase ADC-33 in Acinetobacter baumannii (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1667700] [UniProtKB: B2ZTR6] | ||||||||
| ChEMBL | Activity of Acinetobacter baumannii ADC-33 beta-lactamase | B | 6.3 | pKi | 500 | nM | Ki | Antimicrob Agents Chemother (2010) 54: 3484-3488 [PMID:20547808] |
| Organic anion transporter 4/Solute carrier family 22 member 11 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073677] [GtoPdb: 1030] [UniProtKB: Q9NSA0] | ||||||||
| ChEMBL | TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cells | F | 5.21 | pKi | 6150 | nM | Ki | Eur J Pharmacol (2002) 438: 137-142 [PMID:11909604] |
| Organic anion transporter 1/Solute carrier family 22 member 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1641347] [GtoPdb: 1025] [UniProtKB: Q4U2R8] | ||||||||
| ChEMBL | TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells | F | 5.5 | pKi | 3130 | nM | Ki | Eur J Pharmacol (2002) 438: 137-142 [PMID:11909604] |
| Organic anion transporter 3/Solute carrier family 22 member 8 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1641348] [GtoPdb: 1027] [UniProtKB: Q8TCC7] | ||||||||
| ChEMBL | TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cells | F | 6.54 | pKi | 290 | nM | Ki | Eur J Pharmacol (2002) 438: 137-142 [PMID:11909604] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
