cefotaxime [Ligand Id: 10893] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1730 (Cefotaxime, Cefotaxim hikma) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| ADC-11 in Acinetobacter baumannii (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1667701] [UniProtKB: D6NSM8] | ||||||||
| ChEMBL | Activity of Acinetobacter baumannii ADC-11 beta-lactamase | B | 5.6 | pKi | 2500 | nM | Ki | Antimicrob Agents Chemother (2010) 54: 3484-3488 [PMID:20547808] |
| Beta-lactamase ADC-33 in Acinetobacter baumannii (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1667700] [UniProtKB: B2ZTR6] | ||||||||
| ChEMBL | Activity of Acinetobacter baumannii ADC-33 beta-lactamase | B | 6.3 | pKi | 500 | nM | Ki | Antimicrob Agents Chemother (2010) 54: 3484-3488 [PMID:20547808] |
| Organic anion transporter 4/Solute carrier family 22 member 11 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073677] [GtoPdb: 1030] [UniProtKB: Q9NSA0] | ||||||||
| ChEMBL | TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT4-expressing S2 cells | F | 5.21 | pKi | 6150 | nM | Ki | Eur J Pharmacol (2002) 438: 137-142 [PMID:11909604] |
| Organic anion transporter 1/Solute carrier family 22 member 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1641347] [GtoPdb: 1025] [UniProtKB: Q4U2R8] | ||||||||
| ChEMBL | TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells | F | 5.5 | pKi | 3130 | nM | Ki | Eur J Pharmacol (2002) 438: 137-142 [PMID:11909604] |
| Organic anion transporter 3/Solute carrier family 22 member 8 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1641348] [GtoPdb: 1027] [UniProtKB: Q8TCC7] | ||||||||
| ChEMBL | TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cells | F | 6.54 | pKi | 290 | nM | Ki | Eur J Pharmacol (2002) 438: 137-142 [PMID:11909604] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
