bexmarilimab   Click here for help

GtoPdb Ligand ID: 12907

Synonyms: Clevegen | FP-1305 | FP1305
Immunopharmacology Ligand
Compound class: Antibody
Comment: Bexmarilimab (FP-1305; Faron Pharmaceuticals) is a humanized anti-CLEVER-1 (stabilin 1; STAB1) IgG4-antibody [1]. It switches immunosuppressive M2 macrophages to immune-stimulating M1 macrophages, activates T cells and restores T cell-dependent killing of cancer cells. Bexmarilimab is a cancer immunotherapy clinical candidate [2].
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
11328 bexmarilimab
Synonyms Click here for help
Clevegen | FP-1305 | FP1305
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 1002
Other databases
GtoPdb PubChem SID 485206028
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