Ins(3,4,5,6)P4 [Ligand Id: 4224] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL23050
  • IP3R3/Inositol 1,4,5-trisphosphate receptor type 3 in Human [ChEMBL: CHEMBL3904] [GtoPdb: 745] [UniProtKB: Q14573]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
IP3R3/Inositol 1,4,5-trisphosphate receptor type 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3904] [GtoPdb: 745] [UniProtKB: Q14573]
ChEMBL Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membrane B 6.21 pIC50 620 nM IC50 J. Med. Chem. (1999) 42: 1262-1273 [PMID:10197969]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]