ChEMBL ligand: CHEMBL1090 (ARA-A, Arabinosyladenine, Arasena-a, CI 673, CI-673, NSC-247519, NSC-404241, NSC-757383, Vidarabine, Vidarabine anhydrous, Vidarabine, anhydrous, Vidarabine monohydrate, Vira-a)
S-Adenosylhomocysteine hydrolase/Adenosylhomocysteinase in Mouse [ChEMBL: CHEMBL2389] [GtoPdb: 1233] [UniProtKB: P50247] There should be some charts here, you may need to enable JavaScript!
adenylyl cyclase 5/Adenylate cyclase type V in Rat [ChEMBL: CHEMBL2880] [GtoPdb: 1282] [UniProtKB: Q04400] There should be some charts here, you may need to enable JavaScript!
dipeptidyl peptidase 4/Dipeptidyl peptidase IV in Human [ChEMBL: CHEMBL284] [GtoPdb: 1612] [UniProtKB: P27487] There should be some charts here, you may need to enable JavaScript!
Hepatitis C virus NS5B RNA-dependent RNA polymerase in Hepatitis C virus [ChEMBL: CHEMBL5375] [UniProtKB: Q8JXU8] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
S-Adenosylhomocysteine hydrolase/Adenosylhomocysteinase in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2389] [GtoPdb: 1233] [UniProtKB: P50247]
ChEMBL	Activity determined in mouse liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.	B	4.52	pKi	30000	nM	Ki	J Med Chem (1991) 34: 647-656 [PMID:1995889]
adenylyl cyclase 5/Adenylate cyclase type V in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2880] [GtoPdb: 1282] [UniProtKB: Q04400]
ChEMBL	Compound was evaluated for inhibition of adenylate cyclase from rat brain	B	4.09	pIC50	82000	nM	IC50	J Med Chem (2004) 47: 1207-1213 [PMID:14971900]
dipeptidyl peptidase 4/Dipeptidyl peptidase IV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL284] [GtoPdb: 1612] [UniProtKB: P27487]
ChEMBL	Inhibition of human DPP4 from human Caco-2 cells	B	7.21	pIC50	62	nM	IC50	J Med Chem (2010) 53: 559-572 [PMID:20000418]
Hepatitis C virus NS5B RNA-dependent RNA polymerase in Hepatitis C virus (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5375] [UniProtKB: Q8JXU8]
ChEMBL	Inhibition HCV NS5B-mediated RNA synthesis	F	4.3	pIC50	50000	nM	IC50	J Med Chem (2004) 47: 2283-2295 [PMID:15084127]
ChEMBL	Inhibition HCV RNA replication	F	4.3	pEC50	>50000	nM	EC50	J Med Chem (2004) 47: 2283-2295 [PMID:15084127]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]