Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
CatSper1 in Mouse [GtoPdb: 388] [UniProtKB: Q91ZR5] | ||||||||
GtoPdb | Whole cell patch clamp | - | 3.7 | pIC50 | 200000 | nM | IC50 | Nature (2006) 439: 737-40 [PMID:16467839] |
CatSper2 in Mouse [GtoPdb: 389] [UniProtKB: A2ARP9] | ||||||||
GtoPdb | Whole cell patch clamp. | - | 3.7 | pIC50 | 200000 | nM | IC50 | Mol Hum Reprod (2011) 17: 478-99 [PMID:21642646] |
CatSper3 in Mouse [GtoPdb: 390] [UniProtKB: Q80W99] | ||||||||
GtoPdb | Whole cell patch clamp electrophysiology. | - | 3.7 | pIC50 | 200000 | nM | IC50 | Nature (2006) 439: 737-40 [PMID:16467839] |
CatSper4 in Mouse [GtoPdb: 391] [UniProtKB: Q8BVN3] | ||||||||
GtoPdb | Whole cell patch clamp electrophysiology. | - | 3.7 | pIC50 | 200000 | nM | IC50 | Nature (2006) 439: 737-40 [PMID:16467839] |
TPC1 in Human [GtoPdb: 392] [UniProtKB: Q9ULQ1] | ||||||||
GtoPdb | - | - | 3.74 | pIC50 | 180000 | nM | IC50 | Nat Chem Biol (2014) 10: 463-9 [PMID:24776928] |
TRPA1 in Human [GtoPdb: 485] [UniProtKB: O75762] | ||||||||
GtoPdb | Sodium and calcium imaging | - | 5.85 | pEC50 | 1400 | nM | EC50 |
Proc Natl Acad Sci USA (2009) 106: 8374-9 [PMID:19416844]; Mol Pain (2013) 9: 7 [PMID:23448290] |
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8] | ||||||||
GtoPdb | - | - | 5.68 | pEC50 | 2100 | nM | EC50 |
Proc Natl Acad Sci USA (2009) 106: 8374-9 [PMID:19416844]; Mol Pain (2013) 9: 7 [PMID:23448290] |
TRPC6 in Mouse [GtoPdb: 491] [UniProtKB: Q61143] | ||||||||
GtoPdb | - | - | 3.6 | pIC50 | 253000 | nM | IC50 | Circ Res (2001) 88: 325-32 [PMID:11179201] |
Cav1.1 in Rat [GtoPdb: 528] [UniProtKB: Q02485] | ||||||||
GtoPdb | - | - | 4.3 | pIC50 | - | - | - | J Gen Physiol (1988) 91: 781-98 [PMID:2458429] |
Cav1.2 in Rabbit [GtoPdb: 529] | ||||||||
GtoPdb | - | - | 6 | pIC50 | - | - | - | Am J Physiol (1997) 272: H2164-72 [PMID:9176282] |
Cav2.1 in Rabbit [GtoPdb: 532] | ||||||||
GtoPdb | - | - | 6.3 | pIC50 | - | - | - | |
Cav2.3 in Human [GtoPdb: 534] [UniProtKB: Q15878] | ||||||||
GtoPdb | - | - | 6.1 | pIC50 | - | - | - | J Biol Chem (1994) 269: 22347-57 [PMID:8071363] |
Nav1.7 in Human [GtoPdb: 584] [UniProtKB: Q15858] | ||||||||
GtoPdb | - | - | 3 | pIC50 | - | - | - | EMBO J (1995) 14: 1084-90 [PMID:7720699] |
ASIC2 in Human [GtoPdb: 685] [UniProtKB: Q16515] | ||||||||
GtoPdb | - | - | 3 | pIC50 | ~1000000 | nM | IC50 | Dev Neurobiol (2007) 67: 97-107 [PMID:17443775] |
ClC-4 in Human [GtoPdb: 703] [UniProtKB: P51793] | ||||||||
GtoPdb | - | - | 4.2 | pIC50 | 68000 | nM | IC50 | Biophys J (2008) 95: 4668-75 [PMID:18658230] |
Hv1 in Human [GtoPdb: 746] [UniProtKB: Q96D96] | ||||||||
GtoPdb | - | - | 5 | pIC50 | ~10000 | nM | IC50 | |
Navi2.1 in Human [GtoPdb: 750] [UniProtKB: Q8IZF0] | ||||||||
GtoPdb | - | - | 3.8 | pIC50 | 150000 | nM | IC50 |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.