pyruvic acid [Ligand Id: 4809] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1162144 (2-Oxopropanoate, Pyruvate) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| Dihydrodipicolinate synthase in Escherichia coli (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4083] [UniProtKB: P0A6L2] | ||||||||
| ChEMBL | Inhibition of Escherichia coli dihydrodipicolinate synthase | B | 4.27 | pKi | 54 | uM | Kic | Medchemcomm (2019) 10: 1581-1588 |
| Monocarboxylate transporter 2 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073718] [GtoPdb: 990] [UniProtKB: Q63344] | ||||||||
| ChEMBL | TP_TRANSPORTER: inhibition of lactate uptake in Xenopus laevis oocytes | F | 4.1 | pKi | 80000 | nM | Ki | Biochem J (1999) 341: 529-535 [PMID:10417314] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
