cytarabine

Ligand id: 4827

Name: cytarabine

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 130.83
Molecular weight 243.09
XLogP -0.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1969), EMA (2001))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
International Nonproprietary Names
INN number INN
1709 cytarabine
Synonyms
Cytosar® | DepoCyte® | U-19920
Comments
Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA.
Database Links
CAS Registry No. 147-94-4 (source: Scifinder)
ChEMBL Ligand CHEMBL803
DrugBank Ligand DB00987
GtoPdb PubChem SID 178101529
PubChem CID 6253
RCSB PDB Ligand AR3
Search Google for chemical match using the InChIKey UHDGCWIWMRVCDJ-CCXZUQQUSA-N
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Search UniChem for chemical match using the InChIKey UHDGCWIWMRVCDJ-CCXZUQQUSA-N
Search UniChem for chemicals with the same backbone UHDGCWIWMRVCDJ
Wikipedia Cytarabine